N1o1 Nitric Oxide Lozenge (wholesale)
Enhance Circulation, Vitality, and Overall Wellness
Enhance your health from within. N1o1 Nitric Oxide Lozenges are designed to naturally restore your body’s nitric oxide levels, supporting circulation, energy, and vitality. Backed by groundbreaking Nobel Prize-winning science, these easy to dissolve lozenges promote optimal nitric oxide production, delivering noticeable benefits for your body and mind.
Description
Feel Stronger. Perform Better. Stay Energized.
Your body depends on healthy circulation, endurance, and peak performance to thrive. But as you age, declining nitric oxide production can lead to low energy, reduced stamina, and poor blood flow.
That’s where N1o1 Nitric Oxide Lozenges come in. These powerful lozenges are specially formulated to release nitric oxide as they dissolve, providing numerous benefits to your body. Nitric oxide plays a crucial role in supporting blood flow and circulation, which helps deliver oxygen and nutrients to your muscles and organs. This improved circulation can enhance energy levels, endurance, and overall physical performance—perfect for workouts or staying active throughout the day. Additionally, nitric oxide supports cardiovascular health by relaxing blood vessels, helping to maintain healthy blood pressure. It also aids in improving cognitive function by increasing blood flow to the brain and boosting immune system performance by promoting better cellular communication. With N1o1 Nitric Oxide Lozenges, you can support your body on every level, helping you stay at your best—whether you’re at the gym, at work, or tackling your daily activities. Everyone deserves great blood flow!
Boost Circulatory Health Support Heart Health
Support Brain Function
Support Overall Functions of Your Organ System
The Decline of Nitric Oxide With Age
As we grow older, many bodily functions naturally begin to decline, including the production of nitric oxide. Research shows that by the time you reach 40, your body’s ability to produce nitric oxide can decrease by over 50%.
This decline can have significant effects on overall health, contributing to:
- Stiffened arteries and elevated blood pressure
- Reduced cognitive performance
- Lower exercise capacity and slower recovery
- Declined sexual function
- An increased risk of cardiovascular disease
In the pursuit of longevity and wellness, maintaining optimal nitric oxide levels isn’t just beneficial—it’s essential.
Why N1o1 Is Essential
Why N1o1 Nitric Oxide Lozenges Are Essential for Your Wellness
Created by Dr. Nathan S. Bryan, a leading expert in nitric oxide research, these lozenges are scientifically formulated to optimize your body’s natural processes, improving overall health and performance.
Restore Nitric Oxide Levels Naturally
Restore Nitric Oxide Levels Naturally
Nitric oxide is essential for maintaining healthy circulation, energy, and cardiovascular function. These lozenges help replenish your body’s nitric oxide levels effectively and safely.
Targeted Health Support
Targeted Health Support
Promotes heart health, cognitive clarity, stamina, and overall physical performance by enhancing nitric oxide production.
Backed by Science
Backed by Science
Developed by Dr. Nathan S. Bryan, a world-renowned nitric oxide researcher and leader in biochemistry.
Convenient and Effective
Convenient and Effective
Easy to take, fast-dissolving lozenge that works in the mouth to release Nitric Oxide, designed to fit seamlessly into your daily routine. If you have high acidity levels in your saliva, we recommend mixing baking soda with 2-3 ounces of water and swishing in your mouth for 30-60 seconds prior to taking a lozenge. This will help to alkalize and raise pH levels, therefore reducing the sensitivity to the Vitamin C.
Long-Term Wellness Benefits
Long-Term Wellness Benefits
This is more than a quick boost. Clinical research has shown consistently increasing nitric oxide production can lead to lasting health benefits over time. Support your body’s natural functions with N1o1 Nitric Oxide Lozenges and experience the difference nitric oxide can make over time.
Benefits
Timeline of Physiological Effects Induced by a Nitric Oxide Lozenge
Discover what’s happening in your body when you use a nitric oxide lozenge, from its physiological effects to how it quietly supports your overall health—even if you can’t feel it.
12 Seconds – Carotid arteries begin to dilate, increasing blood flow to the brain.
1 Minute – Blood vessels dilate, enhancing circulation throughout the body.
5 Minutes – Notice a 2.1% boost in exercise performance.
10 Minutes – Carotid arteries dilate by 13%, leading to a 34% increase in blood flow to the brain and body.
20 Minutes – For individuals with elevated blood pressure (130-139/80-89 mmHg), systolic and diastolic blood pressure drops by 5-6 mmHg.
20-30 Minutes – Blood vessels become more flexible and compliant, improving vascular function by 20% and reducing arterial strain.
60 Minutes – Elevated blood pressure drops further by 8-10 mmHg, with some cases seeing reductions of up to 50-60 mmHg for extremely high readings.
4 Hours – Endothelial function improves by 15-25%, boosting natural nitric oxide production.
2 Weeks – Blood flow regulation improves, enhancing mitochondrial function and exercise capacity.
3 Weeks – Reduced oxidative stress and inflammation.
1 Month – Blood pressure in pre-hypertension and hypertension patients decreases by 12 mmHg systolic and 6 mmHg diastolic, triglycerides drop by 27%, and cardiovascular health improves.
6 Months – Existing arterial plaque stabilizes and begins to regress by 11%; endothelial function normalizes.
9 Months – Kidney function improves, protein excretion decreases, and cardiac function strengthens, including reduced cardiac hypertrophy.
12 Months – Arterial health improves, telomeres stabilize, and antioxidant defenses combat post-meal oxidative stress and inflammation. Cognitive gains include better verbal memory and problem-solving skills.
Experience the comprehensive benefits of N1o1 Nitric Oxide Lozenges and transform your cardiovascular health at every stage.
Ingredients
Science Backed Ingredients
164mg Vitamin C (Magnesium Ascorbate)
Provides essential antioxidant support and boosts immune health.
164mg Vitamin C (Magnesium Ascorbate)
Provides essential antioxidant support and boosts immune health.
12.8mg Magnesium (Magnesium Ascorbate)
Reduces tiredness and fatigue while supporting muscle function for optimal physical performance.
12.8mg Magnesium (Magnesium Ascorbate)
Reduces tiredness and fatigue while supporting muscle function for optimal physical performance.
220mg N1o1 Proprietary Blend:
- Magnesium Ascorbate
- Sodium Nitrite
220mg N1o1 Proprietary Blend:
- Magnesium Ascorbate
- Sodium Nitrite
Stevia
A natural ingredient known for its antimicrobial and antioxidant properties, often used to combat skin conditions like acne, reduce signs of aging, and promote overall skin health.
Stevia
A natural ingredient known for its antimicrobial and antioxidant properties, often used to combat skin conditions like acne, reduce signs of aging, and promote overall skin health.
Monk Fruit Extract
A natural ingredient known for its antioxidant and anti-inflammatory properties, often used in skincare to protect against free radicals, reduce inflammation, and promote a healthy, youthful complexion.
Monk Fruit Extract
A natural ingredient known for its antioxidant and anti-inflammatory properties, often used in skincare to protect against free radicals, reduce inflammation, and promote a healthy, youthful complexion.
Other Ingredients:
Mannitol, Microcrystalline Cellulose, Dextrin, Natural Flavors, Croscarmellose Sodium, Maltodextrin, Stearic Acid, Vegetable Stearate, Food Starch - Modified, Starch, Silica, Citric Acid
Other Ingredients:
Mannitol, Microcrystalline Cellulose, Dextrin, Natural Flavors, Croscarmellose Sodium, Maltodextrin, Stearic Acid, Vegetable Stearate, Food Starch - Modified, Starch, Silica, Citric Acid

Watch & Learn
Check out these two informative videos to learn the best way to take the N1o1 Nitric Oxide Lozenge for optimal results.
Dr. Nathan Bryan
Founder of N1o1 Nitric Oxide
Susan Shaffer
President and Co-Founder of N1o1 Nitric Oxide
FAQs
Dr. Bryan
MEET THE FOUNDER
Dr. Nathan Bryan: A Leading Authority on Nitric Oxide
Dr. Nathan S. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Dr. Bryan’s discoveries have led to product and technology innovations that have improved patient care worldwide.
A Pioneer in Nitric Oxide Science
With over 20 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world’s foremost experts on Nitric Oxide’s role in human health.
A Pioneer in Nitric Oxide Science
With over 20 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world’s foremost experts on Nitric Oxide’s role in human health.
Clinically Backed & Scientifically Proven
His discoveries have shaped the field of Nitric Oxide therapy, leading to cutting-edge solutions like the N1o1 Nitric Oxide Lozenges you’re about to experience.
Clinically Backed & Scientifically Proven
His discoveries have shaped the field of Nitric Oxide therapy, leading to cutting-edge solutions like the N1o1 Nitric Oxide Lozenges you’re about to experience.
On a Mission to Improve Lives
Dr. Bryan is dedicated to helping people unlock their body’s full potential through the power of Nitric Oxide—so they can live longer, healthier, and more vibrant lives.
On a Mission to Improve Lives
Dr. Bryan is dedicated to helping people unlock their body’s full potential through the power of Nitric Oxide—so they can live longer, healthier, and more vibrant lives.
Studies
[1] Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria
PubMed
Sandesh C S Nagamani, Philippe M Campeau, Oleg A Shchelochkov, Muralidhar H Premkumar, Kilian Guse, Nicola Brunetti-Pierri, Yuqing Chen, Qin Sun, Yaoping Tang, Donna Palmer, Anilkumar K Reddy, Li Li, Timothy C Slesnick, Daniel I Feig, Susan Caudle, David Harrison, Leonardo Salviati, Juan C Marini, Nathan S Bryan, Ayelet Erez, Brendan Lee
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Download the PDF
[2] The oral microbiome, nitric oxide and exercise performance
PubMed
Nathan S Bryan, Mia C Burleigh, Chris Easton
Nitric Oxide Innovations, LLC, Houston, TX, USA.
Institute for Clinical Exercise and Health Science, University of the West of Scotland, Blantyre, UK.
Download the PDF
[3] Functional Nitric Oxide Nutrition to Combat Cardiovascular Disease
PubMed
Nathan S Bryan
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Alkek Building for Biomedical Research R-850, Houston, TX, 77030, USA.
Read the Study
[4] Nitric oxide enhancement strategies
PubMed
Nathan S Bryan
Department of Molecular & Human Genetics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Private Practice, Chernoff Cosmetic Surgeons, Ascension St. Vincent Hospital, Indianapolis IN, USA
Download the PDF
[5] Oral nitrite therapy improves vascular function in diabetic mice
PubMed
Amy L Sindler, Kimberly Cox-York, Lauren Reese, Nathan S Bryan, Douglas R Seals, Christopher L Gentile
Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA Department of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA.
Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA.
Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA
Download the PDF


